Abstract
The smallest Alzet osmotic minipumps (1007D) were implanted into mouse cerebral cortex. The flow of saline from a minipump produced a large necrosis of cortical tissue and still larger zone of decreased metabolic activity around the site of cannula implantation. Stimulus evoked uptake of 2-deoxyglucose located several millimeters from the implantation site was not affected.
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Copyright (c) 1993 Acta Neurobiologiae Experimentalis
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