Suppression and disinhibition of instrumental alimentary reactions after successive lesions of the dorsomedial and lateral amygdala in dogs (Memorial Paper in Honor of Jerzy Konorski)

Abstract

Damage of the dorsomedial amygdala produced impairment of instrumental performance to CS(+) with no changes to CS(-). Subsequent lesion of the lateral amygdala resulted in restoration of instrumental performance to CS(+) and transient disinhibition to CS(-). These results support the hypothesis that the dorsomedial amygdala is involved in facilitation, while the lateral amygdala in inhibition of alimmentary reactions.