Vitamin D (VD) is a vital liposoluble neurosteroid micronutrient, particularly crucial for women’s health. International literature strongly correlates sufficient VD levels with comprehensive mental well‑being in women. This link is intricately related to neurobiological pathways and hormonal fluctuations, where low VD levels are notably associated with depression. This study comprehensively explores the neurobiological mechanisms that link VD and altered mood in women. Considering the increased susceptibility to hormonal shifts in women, our research investigates the intricate interplay between VD’s neurobiology and mood regulation. Through the focused analysis of specific studies, we untangle the complex web of connections between VD and mood changes in women. Our approach takes into account the dynamic nature of hormonal changes, deepening our understanding of these mechanisms. Our study underscores VD’s significant role as a neurosteroid micronutrient, especially in women’s health. By examining the intricate relationships between VD’s neurobiology and hormones, we propose strategies to improve mood regulation and psychological well‑being in women. In addition, we recommend targeted measures to achieve optimal VD levels, helping to manage challenges arising from hormonal fluctuations. The present review highlights the multifaceted contribution of VD to women’s health, particularly in mood regulation. Through the analysis of the interplay of neurobiology, hormones and VD, our study provides avenues for enhancing women’s mental and emotional well‑being through customized interventions.
This work is licensed under a Creative Commons Attribution 4.0 International License.