Abstract
We review the historical background and principles of the prion theory in its current shape. We showed that most of data may be still interpreted dually according to the protein only hypothesis and according to the theory in which additional component is necessary to comprise the infectivity. The enormous impact of structural biological studies is also stressed.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2002 Acta Neurobiologiae Experimentalis
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