Vol. 54 No. 3 (1994), Articles
Vol. 54 No. 3 (1994)

The effects of lesions of the bed nucleus of the stria terminalis on sodium appetite

Articles
Published 1994-09-30
John Reilly
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104; Clinical Neuroendocrinology Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
Reiko Maki
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104; Clinical Neuroendocrinology Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
Jennifer Nardozzi
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104; Clinical Neuroendocrinology Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
Jay Schulkin
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104; Clinical Neuroendocrinology Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA

Abstract

Lesions of the bed nucleus of the stria termina1is result in decrements in sodium ingestion. Specifically, sodium ingestion that is aroused by mineralocorticoids, in addition to sodium depletion, was reduced in rats with large lesions of the bed nucleus of the stria terminalis. Need-free salt ingestion was also reduced. These results suggest that the bed nucleus of the stria termina1is may be involved in the regulation of sodium appetite.
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Copyright (c) 1994 Acta Neurobiologiae Experimentalis

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