Vol. 54 No. 2 (1994), Articles
Vol. 54 No. 2 (1994)

Expression of astroglial nerve growth factor in damaged brain

Articles
Published 1994-06-30
Barbara Oderfeld-Nowak
Department of Neurophysiology, Nencki Institute of Experimental Biology, 3 Pasteur St., 02-093 Warsaw, Poland
Andrzej Bacia
Department of Neurophysiology, Nencki Institute of Experimental Biology, 3 Pasteur St., 02-093 Warsaw, Poland

Abstract

This article provides an overview of different brain insults leading to induction of astroglial NGF expression. It discusses mechanisms of induction of astroglial NGF in a damaged brain and a possible role of its expression in pathophysiology of Alzheimer's disease. It emphasizes that the pharmacological manipulation of astroglial production of NGF may serve as a possible therapeutic strategy to ameliorate the pathological changes occurring after brain damage.
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 1994 Acta Neurobiologiae Experimentalis

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